The world's first tooth-on-a-chip could revolutionize dentistry

Organ-on-a-chip growing technology is not new. Thanks to her, scientists were able to easily check the effects on the body of potentially dangerous drugs, without resorting to the help of volunteers and experimental animals. To date, artificial versions of the liver, lungs, and pancreas have been created.

And now scientists at Oregon Health and Science University have managed to create a "tooth-on-a-chip". The technology of its cultivation is quite simple. A tiny piece of human dental tissue and a piece of filling material are placed between two thin polymer glasses. At the same time, the space between the glasses is permeated with many microscopic channels through which liquid and bacteria enter the dental tissue.

“Fills don't work well because we can't figure out exactly what's going on at the border of the tooth and the filling, ” explains Professor of Restorative Dentistry Luis E. Bertassoni. - This development will help us solve this problem by providing data on the processes occurring in the tooth in real time.

In a few years, dentists will take a microscopic particle of a tooth from a patient, load it into this device and observe how the filling material interacts with a specific tooth, and based on this, select the material that is best suited for this patient. "