A boy with a rare disease received genetically modified skin

A seven-year-old boy who had 80% of his skin affected by epidermolysis bullosa was treated experimentally by doctors at the Ruhr University in Bochum, replacing the epidermis with genetically modified skin. Epidermolysis bullosa is a serious, incurable disease, as a result of which the skin becomes extremely fragile and vulnerable. Any touch causes excruciating pain in the patient.

In June 2015, the boy was hospitalized with 60% skin lesions. He had sepsis, high fever, and the doctors could do nothing to help him. The only salvation is a new experimental therapy.

First, the researchers took a biopsy of the patient's skin to obtain epidermal stem cells. To correct the existing mutation - the cause of the disease, they were subjected to genetic modification, as a result of which the modified stem cells turned into transgenic skin grafts.

In October, the first transplant was performed, as a result of which the boy felt much better, then several more transplants all over the body followed. In total, 80% of the child's skin was restored.

In February 2016, the operations ended. Doctors note the successful formation of a new epidermis, healthy skin and even the appearance of hair.

This is the first case of such a large-scale transgenic skin transplant in the world, which led to positive results. Now, with good reason, we can talk about a unique method of healing a previously incurable, serious illness.